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Tattoo Medicine explores Pili's path as a brown indigenous Colombian person from the Muisca & Pijao people, highlighting the intersection of ancestral spirituality and healing in his tattoo practice. From his childhood struggles in Miami to being a resident artist at Fruit Camp, the most prominent queer-tattoo shop in Baltimore, the documentary delves into the challenges and triumphs of forging a unique, culturally rooted career in the world of tattooing.